Evaluation of SAS1B as a target for antibody-drug conjugate therapy in the treatment of pancreatic cancer
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چکیده
منابع مشابه
Evaluation of SAS1B as a target for antibody-drug conjugate therapy in the treatment of pancreatic cancer
Successful therapeutic options remain elusive for pancreatic cancer. The exquisite sensitivity and specificity of humoral and cellular immunity may provide therapeutic approaches if antigens specific for pancreatic cancer cells can be identified. Here we characterize SAS1B (ovastacin, ASTL, astacin-like), a cancer-oocyte antigen, as an attractive immunotoxin target expressed at the surface of h...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2018
ISSN: 1949-2553
DOI: 10.18632/oncotarget.23944